Prof. Alison Murdoch
Professor of Reproductive Medicine and Head of Department
- Email: a.p.murdoch@ncl.ac.uk
- Telephone: 0191 2138213
- Fax: +44 (0)191 2138214
- Address: Department of Reproductive Medicine
BioScience Centre
International Centre for Life
Times Square
Newcastle upon Tyne
NE1 4EP
Research Interests
As Head of Newcastle Fertility Centre at Life, my research interests are focussed on improving clinical treatments for infertile couples. Indirectly, the stem cell related studies in the department are achieving this aim. Scientific research within the department is helping to understand the earliest stages of human development from oocyte maturation to the first few days after fertilisation. The donation of eggs, sperm and embryos to support this work is essential and I ensure that we are compliant with all the necessary ethical and regulatory procedures. In this rapidly developing and sensitive field, involvement in the debate, both political and public, is vital to ensure public trust in our work.
Other active research interests include:
• Primary care provision of fertility treatment
• Superovulation protocols and ovarian hyperstimulation syndrome
Selected Publications
- M. Herbert;M. Levasseur;H. Homer;K. Yallop;A. Murdoch;A. McDougall. Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1. Nature Cell Biology 2003, 5(11), 1023-5.
- M. Stojkovic;P. Stojkovic;C. Leary;V. J. Hall;L. Armstrong;M. Herbert;M. Nesbitt;M. Lako;A. Murdoch. Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes. Reproductive Biomedicine Online 2005, 11(2), 226-31.
- Choudhary M, Nesbitt M, Leary C, Murdoch AP. Donation of fresh oocytes for Nuclear Transfer research – A new approach. RBM online 2006, 12(2), 301-302.
- K. Jayaprakasan;M. Herbert;E. Moody;J. A. Stewart;A. P. Murdoch. Estimating the risks of ovarian hyperstimulation syndrome (OHSS): implications for egg donation for research. Human Fertility 2007, 10(3), 183-7.
- Choudhary M; Zhang X; Lako M; Stojkovic M; Murdoch A. "Beauty and Beast" molecule: HA in early human development. BJOG 2009, 116(10), 1408.
- Gurdon J; Murdoch A. Nuclear Transfer and iPS May Work Best Together. Cell Stem Cell 2008, 2(2), 135-138.
